Stearyl-R8

Product Name
Stearyl-R8
Product Quantity
5 mg
Purity
96.46%
Catalog Number
LT12005, LT241707 (96.46%)
Molecular Weight
1533.01
Formula
C66H133N33O9
Sequence Stearyl-RRRRRRRR-NH2
Description

Polyarginine peptides, which are very efficient CPPs have been used for siRNA delivery into cells.

Stearylated octaarginine (Stearyl-R8), are able to encapsulate and shuttle nucleic acids through cell membranes without the need to covalently attach the nucleic acid to the arginine-containing carrier peptide.

Case Study: EGFP-expressing hippocampal neurons

Efficiency: 16 nmol/l siRNA& → 50% reduction in EGFP activity

Reference: Tonges, L, Lingor, P, Egle, R, Dietz, GP, Fahr, A and Bahr, M (2006). Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons. RNA 12: 1431-1438.

See details about the cell penetrating peptides: http://lifetein.com/Cell_Penetrating_Peptides.html

  • 9 Units in Stock

$260.00

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