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Chemical synthesis is an essential part of drug development. LifeTein offers a full range of custom chemical synthesis and manufacturing services to the life science and chemical industries. These include pharmaceutical intermediates, organic chemical materials, APIs, starting materials, and lead compound derivatives. Compounds are made to order in quantities ranging from milligrams to kilograms.

LifeTein offers complete, timely, and cost-effective NMR testing services to meet the requirements of your research and development projects. Routine analysis is typically turned around within 24 hours in our Philadelphia facility.


LifeTein provides medicinal chemistry support services to synthesize target compounds, reference compounds, lead compound derivatives, specialized reagents, and other compounds of interest. Our featured custom requests include, but are not limited to, following:

  • LC/MS service
  • We perform NMR testing for your project reports and publications.
  • Small molecules
  • API's
  • Starting materials, complex intermediates, and final targets
  • Reference compounds and metabolites
  • Combinatorial building blocks
  • Impurities
  • Stable isotope derivatives
  • Libraries
  • Literature and non-literature compounds
  • Large-scale synthesis(up to kg) and commercial manufacturing
Features and Benefits
  • Process Research, Development, and Optimization: Research and development of synthetic pathways for the production of even the most complex molecules and multi-step synthesis pathways;
  • Synthetic Route Design and Optimization: Full literature searches, ensuring that the synthetic route we create for you is the most efficient and optimized route possible
  • Small- and Large-Scale Chemistry Capabilities: Custom synthesis in quantities ranging from milligrams to multi-kilogram orders. We help you bring your projects from idea to production
  • Advanced Synthetic and Analytical Platform: Our chemists work in well-equipped facilities with full access to scientific literature and the reaction databases. We can handle complex distillation, purification, and scale-up protocols
  • Expert Project Management: We keep you up to date on the progress of your projects every step of the way! Expect weekly project updates as your order moves toward completion
  • Green Chemistry Synthesis: We have replaced dangerous and environmentally unfriendly steps during chemical synthesis
  • Low Cost and High Efficiency: We carefully reduced the number of steps to lower costs and increase the efficiency, yield, and throughput of the process
Synthesis Technologies

LifeTein has committed ourselves to using and developing advanced chemical technologies that allow us to fulfill this goal. Our chemical technology base is therefore constantly growing.

LifeTein has expertise in the following areas:

  • Chiral synthesis
  • Polymer chemistry
  • Air-sensitive and moisture-sensitive chemistry
  • Metal-mediated reactions
  • Hydrogenations
  • Grignard reactions
  • Solid phase synthesis (Peptides)
  • Methylations
  • Liquid-phase synthesis (Peptides)
  • Nitrations
  • Aminations
  • Nitrosations
  • BOC-protection

Outsourcing your chemical synthesis needs to LifeTein is an efficient, cost-effective way to ensure the timely progress of your drug development projects. We offer prompt quotations, very competitive prices, high-quality products, and fast delivery.


Alapan et al., Sci. Robot. 5, eaba5726 (2020), 20 May 2020

...A functional o-nitrobenzyl photocleavable linker [1-(5-methoxy2-nitro-4-prop-2-ynyloxyphenyl)ethyl N-succinimidyl carbonate, LifeTein LLC, Somerset, NJ)] was conjugated to the amino end of the microrollers by NHS-amino coupling chemistry. ...

Science, 24 Jul 2020: Vol. 369, Issue 6502, pp. 423-426, DOI: 10.1126/science.abb3457

...Molecule H1 was commercially synthesized by LifeTein, LLC, following the same synthesis steps reported in 23...

Chemical synthesis service

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