Proteins

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Featured Proteins of Coronavirus Disease 2019 (COVID-19): SARS-CoV-2 Spike RBD Protein, Nucleocapsid Protein, ACE2 Protein

2019 Novel Coronavirus SARS-CoV-2 is a virus identified as the cause of an outbreak of respiratory illness Covid-19 first detected in Wuhan, China.

The coronavirus Nucleocapsid (N) of Coronavirus forms the helical ribonucleocapsid complexes with positive strand viral genomic RNA. It plays an important role in virus replication, transcription, and assembly.

The coronavirus Spike protein (S) is a large oligomeric transmembrane protein that mediates coronavirus entry into host cells. It contains S1 and S2 two subunits. The receptor-binding domain (RBD) of the S1 subunit recognizes host cell surface receptors. S2 subunit is responsible for the membrane fusion.

The Covid-19 uses the cellular Angiotensin converting enzyme 2 (ACE2) protein as a receptor for cellular entry.

Order PepMag Magnetic Agarose beads for easy peptide conjugation, pull down experiment and binding assays. Simply mix the agarose beads with your peptide through reactions with the amine groups on the peptide. The high surface area of porous magnetic agarose beads results in high binding capacities. The binding of peptide and agarose beads are permanent. For binding with your target protein or antibody, simply mix the conjugated beads with your samples, Wash the beads and elute the protein or antibody using 50 mM glycine pH 2.5. Any buffer that breaks the binding between peptide/protein or peptide/antibody can be used for elution.

Highlights

LTCY-0001	Mannose-6-phosphate isomerase	$1500 $950
LTCN12115	Human Sphingomyelin synthase 1, recombinant	$9,000
LTCN12116	Human Sphingomyelin synthase 2, recombinant	$9,000
LT12014	Alkali-tolerant Recombinant Protein A Conjugated to Agarose Resin	$280    $150
LT13512	Protein A Magnetic Agarose Resin	$280
LT13513	Peptide Conjugation Magnetic Agarose Resin	$280
LT12015	Recombinant Protein G Conjugated to Agarose Resin	$350    $165
LT12010	Recombinant Human Copper, Zinc-Superoxide Dismutase	$230

LifeTein provides special protein products including Alkali-tolerant Protein A, Protein G, streptavidin, human fibroblast growth factors, human vascular endothelial growth factor, human growth hormone, and human copper, zinc-superoxide dismutase.

Protein A is derived from Staphylococcus aureus. Protein G is derived from a Streptococcus species. Both have binding sites for the Fc portion of mammalian IgG. Protein G has a higher affinity for rat, goat, sheep, and bovine IgG, as well as for mouse IgG1 and human IgG3. Protein A has a higher affinity for cat and guinea pig IgG. Protein G is recommended for most species, including mouse and rat. Protein A is recommended for cat and guinea pig. Neither is recommended for detection of IgA or IgM, for detection of Fab fragments, or for detection of avian IgG.

Streptavidin is a tetrameric protein which binds very tightly to the small molecule, biotin. The binding constant for this interaction is very high and has made the streptavidin/biotin system the tool for intermolecular interactions.

Fibroblast Growth Factor-basic (FGF-b) is a heparin binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells.

LifeTein's recombinant Superoxide Dismutase belongs to Human Copper, Zinc-Superoxide Dismutase (rh-SOD1). Superoxide dismutase is a metalloenzyme. This enzyme binds to molecules of copper and zinc to break down toxic, charged oxygen molecules called superoxide radicals.

Protein Products:

Cat. No	Product Name	Price	Download Data Sheet	Order
LT12008	Recombinant Staphylococcal Protein A	$238 $158
LT12014	Alkali-tolerant recombinant Protein A Agarose Resin	$280 $150
LT12007	Recombinant Streptococcus Protein G	$280 $198
LT12015	Recombinant Protein G Agarose Resin	$350 $165
LT13512	Protein A Magnetic Agarose Resin	$280
LT13513	Peptide Conjugation Magnetic Agarose Resin	$280
LT12009	Recombinant Streptavidin (r-SA)	$330 $158
LT12012	Recombinant Human Fibroblast Growth Factor-Basic	$380 $290
LT12012-02	Recombinant Human Fibroblast Growth Factor Basic Agarose	$500 $350
LT12011	Recombinant Human Vascular Endothelial Growth Factor	$370
LT12011-02	Recombinant Human Vascular Endothelial Growth Factor Agarose	$500 $350
LT12013	Recombinant Human Growth Hormone	$220
LT12010	Recombinant Human Copper, Zinc-Superoxide Dismutase	$230

Affinity of Protein A/G for IgG Types from Different Species