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Featured Proteins of Coronavirus Disease 2019 (COVID-19): SARS-CoV-2 Spike RBD Protein, Nucleocapsid Protein, ACE2 Protein
2019 Novel Coronavirus SARS-CoV-2 is a virus identified as the cause of an outbreak of respiratory illness Covid-19 first detected in Wuhan, China.
The coronavirus Nucleocapsid (N) of Coronavirus forms the helical ribonucleocapsid complexes with positive strand viral genomic RNA. It plays an important role in virus replication, transcription, and assembly.
The coronavirus Spike protein (S) is a large oligomeric transmembrane protein that mediates coronavirus entry into host cells. It contains S1 and S2 two subunits. The receptor-binding domain (RBD) of the S1 subunit recognizes host cell surface receptors. S2 subunit is responsible for the membrane fusion.
The Covid-19 uses the cellular Angiotensin converting enzyme 2 (ACE2) protein as a receptor for cellular entry.
Peptides for COVID-19 Research
| LT5578 | 2019 Coronavirus SARS-CoV-2 Receptor Binding Motif | $1000, In Stock |
| LT5587 | Coronavirus SARS-CoV-2 Surface Glycoprotein, 74 amino acids | $1000, In Stock |
| LT-V007 | SBP1: Peptide binder to the SARS-CoV-2 spike protein | $450, In Stock |
| LT-V008 | Biotin-SBP1: Biotin-Peptide binder to the SARS-CoV-2 spike protein | $450, In Stock |
| LT-V012 | SARS-CoV-2 Receptor Binding Domain Overlapping Peptide Library, 22 Peptides, 15mer, 5 amino acid overlapping | $1980, In Stock |
| LT-V013 | SARS-CoV-2 Receptor Binding Domain Peptide Library, 4 Peptides, 20mer without overlapping | $499, In Stock |
| LT-V014 | Angiotensin-converting enzyme 2 (ACE2) substrates and peptides | Call for Quote, 2-3 weeks |
| LT-V015 | Aviptadil (Senatek), Vasoactive intestinal polypeptide | Call for Quote, 2-3 weeks |
Proteins for COVID-19 Research
| LTP-V001 | Coronavirus SARS-CoV-2 Nucleocapsid Protein, DYKDDDDK tag | |
| LTP-V002, 50ug | 50ug, Coronavirus SARS-CoV-2 Spike RBD Protein, human IgG1 Fc tag | |
| LTP-V002, 1mg | 1mg, Coronavirus SARS-CoV-2 Spike RBD Protein, human IgG1 Fc tag | |
| LTP-V009, 50ug | 50ug, Coronavirus SARS-CoV-2 Spike RBD Protein, polyhistidine tag | |
| LTP-V009, 1mg | 1mg, Coronavirus SARS-CoV-2 Spike RBD Protein, polyhistidine tag | |
| LTP-V003 | Recombinant Human ACE2 Protein, human IgG1 Fc tag | |
| LTP-V004, Discontinued, Extremely Low Yield | Recombinant SARS-CoV-2 Spike S2 Protein, polyhistidine tag | Discontinued |
| LTP-V005 | Recombinant Human ACE2 Protein (H374N, and H378N), human IgG1 Fc tag | |
| LTP-V006, Discontinued, Low binding to ACE2 receptor | Recombinant SARS-CoV-2 Spike S1 Protein, polyhistidine tag | Discontinued |
Antibodies for COVID-19 Research
| LTA-V010 | Monoclonal Antibodies Against 2019 Coronavirus SARS-CoV-2 Receptor Binding Motif (A 74 Amino Acid Immunogen) | Under Development |
| LTA-V011 | Monobodies Against 2019 Coronavirus SARS-CoV-2 Spike RBD Protein | Under Development |
Order PepMag Magnetic Agarose beads for easy peptide conjugation, pull down experiment and binding assays. Simply mix the agarose beads with your peptide through reactions with the amine groups on the peptide. The high surface area of porous magnetic agarose beads results in high binding capacities. The binding of peptide and agarose beads are permanent. For binding with your target protein or antibody, simply mix the conjugated beads with your samples, Wash the beads and elute the protein or antibody using 50 mM glycine pH 2.5. Any buffer that breaks the binding between peptide/protein or peptide/antibody can be used for elution.
Highlights
| LTP4418 | Recombinant Mouse TRANCE/RANK L/TNFSF11 |  |
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| LTCY-0001 | Mannose-6-phosphate isomerase | |
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| LTCN12115 | Human Sphingomyelin synthase 1, recombinant | $9,000 | |
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| LTCN12116 | Human Sphingomyelin synthase 2, recombinant | $9,000 | |
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| LT16323 | Thiol-Activated Peptide Conjugation Magnetic Beads | $320 | |
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| LT13513 | Amine-activated Peptide Conjugation Magnetic Beads | $320 | |
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| LT12010 | Recombinant Human Copper, Zinc-Superoxide Dismutase | $230 | |
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LifeTein provides special protein products including Alkali-tolerant Protein A, Protein G, streptavidin, human fibroblast growth factors, human vascular endothelial growth factor, human growth hormone, and human copper, zinc-superoxide dismutase.
Protein A is derived from Staphylococcus aureus. Protein G is derived from a Streptococcus species. Both have binding sites for the Fc portion of mammalian IgG. Protein G has a higher affinity for rat, goat, sheep, and bovine IgG, as well as for mouse IgG1 and human IgG3. Protein A has a higher affinity for cat and guinea pig IgG. Protein G is recommended for most species, including mouse and rat. Protein A is recommended for cat and guinea pig. Neither is recommended for detection of IgA or IgM, for detection of Fab fragments, or for detection of avian IgG.
Streptavidin is a tetrameric protein which binds very tightly to the small molecule, biotin. The binding constant for this interaction is very high and has made the streptavidin/biotin system the tool for intermolecular interactions.
Fibroblast Growth Factor-basic (FGF-b) is a heparin binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells.
LifeTein's recombinant Superoxide Dismutase belongs to Human Copper, Zinc-Superoxide Dismutase (rh-SOD1). Superoxide dismutase is a metalloenzyme. This enzyme binds to molecules of copper and zinc to break down toxic, charged oxygen molecules called superoxide radicals.
Protein Products:
Cat. No |
Product Name |
Price |
Download Data Sheet |
Order |
| LT12008 | Recombinant Staphylococcal Protein A | |
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| LT12014 | Alkali-tolerant recombinant Protein A Agarose Resin | |
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| LT12007 | Recombinant Streptococcus Protein G | |
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| LT12015 | Recombinant Protein G Agarose Resin | |
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| LT13512 | Protein A Magnetic Agarose Resin | $280 | |
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| LT13513 | Peptide Conjugation Magnetic Agarose Resin | $280 | |
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| LT12009 | Recombinant Streptavidin (r-SA) | |
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| LT12012 | Recombinant Human Fibroblast Growth Factor-Basic | |
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| LT12012-02 | Recombinant Human Fibroblast Growth Factor Basic Agarose | |
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| LT12011 | Recombinant Human Vascular Endothelial Growth Factor | $370 | |
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| LT12011-02 | Recombinant Human Vascular Endothelial Growth Factor Agarose | |
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| LT12013 | Recombinant Human Growth Hormone | $220 | |
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| LT12010 | Recombinant Human Copper, Zinc-Superoxide Dismutase | $230 | |
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Affinity of Protein A/G for IgG Types from Different Species
| Species | Immunoglobulin | Binding to Protein A | Binding to Protein G |
|---|---|---|---|
| Human | lgG (normal) | ++++ | ++++ |
| lgG1 | ++++ | ++++ | |
| lgG2 | ++++ | ++++ | |
| lgG3 | - | ++++ | |
| lgG4 | ++++ | ++++ | |
| lgM | - | - | |
| lgA | - | - | |
| lgE | - | - | |
| Mouse | lgG1 | + | ++++ |
| lgG2a | ++++ | ++++ | |
| lgG2b | +++ | +++ | |
| lgG3 | ++ | +++ | |
| Rat | lgG1 | - | + |
| lgG2a | - | ++++ | |
| lgG2b | - | ++ | |
| lgG2c | + | ++ | |
| Goat | lgG | +/- | ++ |
| Rabbit | lgG | ++++ | +++ |
| Sheep | lgG | +/- | ++ |