Human CCR2b Protein-VLP (LTP10415)

Product Name
Human CCR2b Protein-VLP (LTP10415)
Catalog Number
LTP10415
Quantity
100ug
Price
$2250 In stock
Background
The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane structures.
Description
Recombinant Human CCR2b Protein-VLP is expressed from Expi293. It contains Met1-Leu360.
Target
CCR2b
Species
Human
Gene/Protein ID
P41597-2
Exact Sequence
Met1-Leu360
Molecular Weight
The target protein has a predicted MW of 42.9kDa.
Activity
Immobilized Human CCR2b VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CCR2b Antibody, hFc Tag with the EC50 of 12.0ng/ml determined by ELISA. See testing image for detail.
Tag
0
Express System
Expi293
Purity
> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human CCR2b Protein-VLP (LTP10415)
  • 5 Units in Stock

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