LifeTein provides high-quality custom peptide synthesis services for researchers in academia, biotechnology, pharmaceutical development, diagnostics, and related fields. We support both standard and challenging peptide projects with reliable analytical quality, responsive technical communication, and a broad range of peptide modification options.
| Purity options | Crude, desalted, >75%, >85%, >95%, >98%, and higher purity upon request |
| Peptide length | 2 to 170 amino acids, including long peptides exceeding 100 amino acids |
| Turnaround | Standard peptide synthesis is typically completed in 2–3 weeks; rush service is available for selected projects |
| Quality control | Analytical HPLC and mass spectrometry; standard package includes Certificate of Analysis, HPLC report, and MS report |
| Available modifications | Biotinylation, phosphorylation, fluorescent labeling, PEGylation, stapled peptides, oligonucleotide conjugation, glycosylation, TFA removal, and other custom modifications |
LifeTein® has developed a proprietary technology called PeptideSynTM. This platform combines Fmoc and Boc chemistry, specialized solid support resins, a bio-inert HPLC system, and microwave technology to support efficient peptide synthesis with consistent quality and competitive pricing.
We have extensive experience synthesizing peptides across a broad range of sequence lengths and complexities, including peptides that exceed 100 amino acids. Notable achievements include a 76aa BfUbb peptide, a 97aa peptide mB Box-97syn, a 133aa SHT peptide, and a 169aa long peptide. All peptides are verified by HPLC purification and molecular weight confirmation using Electrospray Ionization (ESI) mass spectrometry.
Many peptide projects are straightforward, while others require more careful planning because of hydrophobic residues, aggregation tendencies, unusual amino acid composition, long sequence length, or specialized modifications. LifeTein supports challenging peptide projects including hydrophobic peptides, long peptides, heavily modified peptides, and peptides used in conjugation, assay, and delivery applications.
LifeTein offers a broad portfolio of peptide synthesis formats and modifications, including Peptide Oligo Conjugates by Click Chemistry, Stapled Peptides, Lipid Nanoparticles, Stable Isotope Labeled Peptides, Peptide Nucleic Acids, Fluorescent Peptides, Phosphorylated Peptides, Glycosylated Peptides, Peptide Pool Services, Biotinylated Peptides, Cell-Permeable Peptides, Cyclic Peptides, MAP Peptide Synthesis, and D Amino Acid Peptides.
Click here to see the full list of peptide modifications and labeling options.
Reference:
NUCLEIC ACID VECTORS AND USES THEREOF: LifeTein synthesized a peptide of 133 amino acids. The peptide sequence includes at least one cell-permeable peptide (CPP) domain, one secretion signal sequence, one DNA binding domain, and other SHT protein.
Need a quote for your peptide?
Send us your sequence, target purity, quantity, and any desired modification. Our team will review your project and respond promptly.
Explore LifeTein’s peptide formats, modification options, technical capabilities, FAQs, and example applications below.
Phosphorylation: Tyr-, Ser-, and Thr-phosphorylated peptides for signal transduction, protein interaction, and assay development.
Biotinylation: Peptides with strong streptavidin and avidin affinity for immunoassays, histochemistry, and flow cytometry applications.
Cyclization: Disulfide, head-to-tail, amide, and thioester cyclization strategies to stabilize peptide conformation and improve peptide activity.
Long Peptide Synthesis: Long peptide production as an alternative to exogenous protein expression for selected research applications.
Cell-Permeable Peptides: Deliver biologically active cargo to the cell interior and cross the plasma membrane independent of a membrane receptor.
Linkers, Spacers, and PEGylation: Improve peptide accessibility, reduce steric hindrance, and enhance peptide stability and solubility.
Fluorescent Labeling: FITC, FAM, TAMRA, Rhodamine, Dansyl, Dnp, Mca, Cy3, Cy5, and Cy7 for fluorescence assays, flow cytometry, localization studies, and interaction analysis.
Short Peptide Synthesis: Dipeptides and tripeptides for signaling studies, screening projects, and selected cosmetic applications.
D Amino Acid Peptides: Protease-resistant peptides with enhanced stability for peptide design and selected therapeutic research applications.
TFA-Free / Acetate Peptides: Peptide salt exchange options for applications requiring lower TFA content, including cell studies and peptide drug research.
Rush Peptide Service: Accelerated peptide delivery for selected projects when time is critical.
Peptide Magnetic Agarose Conjugate: Conjugate peptides to magnetic agarose for binding assays and pull-down applications.
N-Terminal Acetylation: Improve peptide stability and reduce susceptibility to N-terminal degradation.
C-Terminal Amidation: Neutralize the C-terminal negative charge, better mimic native peptide forms, and reduce unwanted hydrogen-bonding effects.
Multiple Antigenic Peptides (MAP), Dendrimers, and Dendrons: Branched peptide formats such as MAP4 or MAP8 for higher peptide antigen density and stronger immune responses.
Immunogenic Peptides: BSA, KLH, or OVA Conjugation: Conjugated peptides for ELISA development and antibody production projects.
Peptide Library: Large-scale peptide screening formats for discovery projects and lead identification.
Stapled Peptides, Glycosylation, and Special Amino Acids: Specialized amino acids and modifications for stability, membrane interaction, and advanced peptide design.
FRET Peptides: Peptides labeled for fluorescence resonance energy transfer studies and enzymatic assay development.
Disulfide Bond Peptides: Peptides containing disulfide bonds for structural stabilization and native conformation studies.
Frequently Asked Questions: Peptide Synthesis
Introducing medicines into cells has long been a challenge in research. Cell-penetrating peptides (CPPs) can enter cells through the plasma membrane independent of a membrane receptor and are often small peptides of approximately 10–30 residues.
Stapled Peptide Synthesis Service
Click here or the image below for more details.
The following table shows a selection of currently known CPPs together with their origins and sequences. Click here for more details. See also additional case studies.
Name |
Sequence |
HIV-1 protein |
GRKKRRQRRRPPQQ |
Stearyl-R8 |
Stearyl-RRRRRRRR-amide |
Please fax our order form to 1-888-791-1618 or email us at peptide@lifetein.com.
1. Pricing examples
You can use the following table to estimate peptide synthesis pricing. Please inquire for more detailed pricing information.
| Quantity | Purity | ||
| Crude | >85% (Get a quote for desalted, 75%, 80%, and other purities) | >95% (Get a quote for >98%, 99%, and other purities) | |
|
1–4 mg (Get a quote for 5–9 mg, 10–14 mg, and other quantities) |
$3.20 | $9.00 | $11.56 |
| 15–20 mg | $4.76 | $15.30 | $20.40 |
| 40–50 mg | $6.46 | $19.89 | $27.20 |
| 70–80 mg | $7.82 | $26.69 | $35.70 |
| 1000 mg | $28.05 | $79.90 | $105.40 |
Click here to see the list of available peptide modifications
2. How to request a quotation
3. How to place an order
