FITC-Strearyl-R8

Product Name
FITC-Stearyl-R8
Product Quantity
1mg
Purity
95.89%
Catalog Number
LT12013
Molecular Weight
2107.64
Formula
C95H159N37O16S
Sequence CH3(CH2)16-CONH-RRRRRRRRGK(FITC)-NH2
Description

Polyarginine peptides, which are very efficient CPPs have been used for siRNA delivery into cells. This product has FITC labeled on the side chain of Lysine at the C terminus. Glycine is added as a linker for FITC labeling. The product can be used as a control to monitor the peptide entry.

Stearylated octaarginine (Stearyl-R8), are able to encapsulate and shuttle nucleic acids through cell membranes without the need to covalently attach the nucleic acid to the arginine-containing carrier peptide.

Case Study: EGFP-expressing hippocampal neurons

Efficiency: 16 nmol/l siRNA& → 50% reduction in EGFP activity

Reference: Tonges, L, Lingor, P, Egle, R, Dietz, GP, Fahr, A and Bahr, M (2006). Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons. RNA 12: 1431-1438.

See details about the cell penetrating peptides: https://lifetein.com/Cell_Penetrating_Peptides.html

  • 7 Units in Stock

$250.00  $150.00
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