Biomolecule Peptide Conjugation Services

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Peptide Modifications

LifeTein provides a wide range of peptide modification services and biomolecule peptide conjugation services.

LifeTein provides peptide-macromolecule bioconjugation service. The service allows for the conjugation of oligonucleotides, fluorescent dyes, chromogenic enzyme substrates, drugs, toxins, or carrier proteins to the peptides. The peptide can be conjugated to the molecules through the chemical reactive groups such as amine, thiol, or carboxylate.

LifeTein's service portfolio includes peptide oligo conjugates for gene inhibition, siRNA delivery, cellular entry, protein to protein interaction, nucleic acid-protein interaction, or drug delivery; peptide antibody conjugates for drug therapy, diagnostics and microarray detection, or therapeutic drug discovery; biotin peptide conjugates for immunoassay, or pull down assay; and synthetic polymers for pegylation, dendrimers, nanoparticles, or gold particles.

  • Oligo peptide conjugates: DNA conjugates, RNA conjugates, siRNA conjugates
  • Peptide-Antibody Conjugation
  • Dendritic Peptide
  • Peptide-Drug Conjugates
  • Peptide-Protein Conjugation

Click here to download the LifeTein Peptide Modification Full List

N Terminus
  • {Ac},Acetylation (Free)
  • {For}, Formylation
  • {Fmoc}, 9-Fluorenylmethyloxycarbonyl
  • {Suc}, succinyl;{MeO-Suc}
  • {Cl-Ac}, Chloroacetyl
  • {Mal}, Maleimide
  • {CBZ}, Benzyloxycarbonyl
  • {Br-Ac}, Bromoacetyl
  • Nitrilotriacetyl
  • {Boc}, tertbutoxycarbonyl
  • {HPP}, 4-Hydroxyphenylpropionic acid
  • {LA}, Lipoic acid
  • {mPEG2000}, {mPEG3000}, {mPEG5000}, Mal-PEG12
  • {Alloc}, allyloxycarbonyl
  • {Boc}, tertbutoxycarbonyl
  • {But}, Butyric acid
  • {Hex}, Hexanoic acid
  • {Oct}, Octanoic acid
  • {Dec}, Decanoic acid
  • {Pal}, Palmitic acid
  • {Ste}, Stearic acid
  • {Myr}, Myristic acid
  • {Lau}, Lauric acid
  • More...
  • {NH2}, Amidation (Free)
  • {CHO}, Peptide Aldehydes
  • {OL}, Alcohol Peptide
  • {CMK}, Chloromethylketone
  • {AMC}, 7-Amino-4-Methylcoumarin
  • {pNA},p-Nitroaniline
  • {-ONP}, para-nitrophenol
  • {-OSu}, hydroxysucinimide ester
  • ED, {AFC}, -OMe, -OtBu
  • {FMK}, Fluoromethylketone
  • {Cya}, Cysteamide
  • More...
  • {D-Ala}
  • {D-Arg}
  • {D-Asp}
  • {D-Asn}
  • {D-Cys}
  • {D-Glu}
  • {D-Gln}
  • {D-His}
  • {D-Allo-Ile}
  • {D-Leu}
  • {D-Lys}
  • {D-Met}
  • {D-Pro}
  • {D-Phe}
  • {D-Ser}
  • {D-Tyr}
  • {D-Thr}
  • {D-Trp}
  • {D-Val}
  • More...
  • {Cys(Cam)}
  • {D-Cys(Cam)
  • {Cys(Acm)}
  • {Cys(tBu)}
  • {Cys(StBu)}
  • {Cys(Nitosothiols)}
  • {Cys(Pyrene-Maleimide)}
  • {Gamma-Glu}
  • {D-Gamma-Glu}
  • {Beta-Asp}
  • {D-Beta-Asp}
  • {Met(O)}
  • {D-Met(O)}
  • {Lys(Ac)}
  • {Ac-Lys}
  • {Lys(Dde)}
  • {Gly(allyl)}
  • {D-Gly(allyl)}
  • {Cpg}, Cyclopentylglycine
  • {Tle}
  • {Ser(Octanoic acid)}
  • {Ser(Lipoic acid)}
  • {D-Ser(Octanoic acid)}
  • {3-Ala(2-thienyl)-OH}
  • {3-Ala(3-thienyl)-OH}
  • {Aib}
  • {Abu}
  • {D-Abu}
  • {Hyp}
  • {Phg}
  • {D-Phg}
  • {Nva}
  • {D-Nva}
  • {Nle}
  • {D-Nle}
  • {Cit}
  • {D-Cit}
  • {Orn}
  • {D-Orn}
  • {Pen}
  • {D-Pen}
  • {Cha}
  • {D-Cha}
  • {Chg}
  • {D-Chg}
  • {Dab}
  • {Dap}
  • {Pra}
  • {D-Pra}
  • {Allo-Thr}
  • {D-Allo-Thr}
  • More...
  • Cyanine 3, Cyanine 5, Cyanine 5.5, Cyanine 7, Cyanine 7.5, BDP 581/591, cy3, cy5, Texas Red, More details
  • Alexa Fluor 350, Alexa Fluor 405, Alexa Fluor 488, Alexa Fluor 532, Alexa Fluor 546, Alexa Fluor 555, Alexa Fluor 568, Alexa Fluor 594, Alexa Fluor 647, Alexa Fluor 680, Alexa Fluor 750
  • Qdot 525, Qdot 565, Qdot 605, Qdot 655, Qdot 705, Qdot 800
  • Biotin (N terminus)
  • DeThioBiotin
  • EDBiotin (C terminus)
  • Lys(Biotin) (middle)
  • Lys(Biotin) (C terminus)
  • Lys(LC-Biotin) (middle)
  • Lys(LC-Biotin) (C terminus)
  • Lys(Biotin) (N terminus)
  • Biotin-LC (N terminus)
  • FITC (N terminus)
  • Lys(FITC) (middle)
  • Lys(FITC) (C terminus)
  • Lys(FITC) (N terminus)
  • FITC-LC (N terminus)
  • 5-FAM (N terminus)
  • 6-FAM (N terminus)
  • Lys(5-FAM) (middle)
  • Lys(5,6-FAM)
  • Lys(5-FAM) (C terminus)
  • Lys(5-FAM) (N terminus)
  • 5-FAM-LC (N terminus)
  • Dansyl (N terminus)
  • EDDansyl (C terminus)
  • Lys(Dansyl) (middle)
  • Lys(Dansyl) (C terminus)
  • Lys(Dansyl) (N terminus)
  • Dansyl-LC (N terminus)
  • TAMRA (N terminus)
  • 5(6)-TAMTA-
  • EDTAMRA (C terminus)
  • Lys(TAMRA) (middle)
  • Lys(TAMRA) (C terminus)
  • Lys(TAMRA) (N terminus)
  • TAMRA-LC (N terminus)
  • Lys(Dnp) (middle)
  • D-Lys(Dnp) (middle)
  • Dab(Dnp) (middle)
  • Dap(Dnp) (middle)
  • EDDnp (C terminus)
  • MCA (N terminus)
  • Lys(MCA) (middle)
  • Lys(MCA) (C terminus)
  • Lys(MCA) (N terminus)
  • 3-Indolylacetic acid (N terminus)
  • Cys(Npys) (N terminus)
  • PyBA- (N terminus), 1-pyrenebutyric acid
  • Lys(PyBA)
  • Fa- (N terminus), 3-[2-2furyl]acrylic acid
  • Rhodamine B- (N terminus)
  • Lys(Rhodamine B)
  • More...
  • {Gly}, 2 Carbons
  • {Beta-Ala}, 3 Carbons
  • {GABA}, 4 Carbons
  • {Ava}, 5 Carbons
  • {Ahx}, 6 Carbons
  • {AEA},Aminoethoxyacetic Acid
  • {Mini-PEG}, 9 Carbons
  • {Mini-PEG2}, 13 Carbons
  • {Mini-PEG3}, 16 Carbons
  • {ANP Linker}
  • More details
  • {Cys(Me)}, SMC
  • {ADMA}, {Arg(Me)2} asymmetrical
  • {SDMA}, {Arg(Me)2} symmetrical
  • {Arg(Me)}
  • {Thr(Me)}
  • {Ser(Me)}
  • {Lys(Me)}
  • {Lys(Me2)}
  • {Lys(Me3)}
  • {L-1-Me-Trp}
  • {L-2-Me-Trp}
  • {D-2-Me-Trp}
  • {Tyr(Me)}
  • {Tyr(Et)}
  • {D-Tyr(Et)}
  • {Orn(Me)3}
  • {N-Me-Gly}, Sar
  • {N-Me-Ser}
  • {N-Me-Tyr}
  • {N-Me-Thr}
  • {N-Me-Asp}
  • {N-Me-Glu}
  • {N-Me-Ala}
  • {N-Me-Phe}
  • {N-Me-Leu}
  • {N-Me-Ile}
  • {N-Me-Val}
  • {N-Me-Met}
  • {N-Me-Nle}
  • {N-Me-Nva}
  • More...
  • {pSer}
  • {D-pSer}
  • {pTyr}
  • {D-pTyr}
  • {pThr}
  • {D-pThr}
  • 2, 3 or 4 phosphorylation sites in the sequence
  • More...
  • Up to 10 Free Aliquots (Why Aliquot?)
  • Free HPLC Data
  • Free MS Data
  • Free Certificate Of Analysis (COA)
  • Convert from TFA Salt to Acetate Salt or Hydrochloride Salt
  • Amino Acid Analysis
  • N Elemental Analysis
  • Solubility Test
  • Bioburden
  • Water Content
  • Bacterial Endotoxins
  • More...

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