Publication-Grade Peptides

Publication-Grade Peptides: Selected Examples from the Literature

Publication-grade peptides from LifeTein

LifeTein peptides have been cited in many peer-reviewed publications, including studies requiring long peptide synthesis, fluorescent labeling, phosphopeptides, biotinylated peptides, cyclic peptides, and other challenging custom formats. This page highlights representative peptide capability areas rather than trying to function as a broad publications archive.

Featured example: Nature Communications (2026)

In a recent study on IRF2BPL, LifeTein synthesized two difficult custom peptides: a 54 amino acid peptide with N-terminal acetylation, C-terminal amidation, and >95% purity, and a 75 amino acid peptide with an N-terminal FITC tag linked through a 6-aminohexanoic acid (Ahx) spacer, C-terminal amidation, and >90% purity.

Selected Capability Areas

  • Long peptides and difficult sequences
  • Fluorescently labeled peptides
  • N-terminal acetylation and C-terminal amidation
  • Biotin, Ahx, and linker-modified peptides
  • Phosphopeptides and PTM-containing peptides
  • Cyclic and constrained peptide formats
  • Peptides for protein interaction studies
  • Peptide tools for antibody generation and validation

For the broader references archive, see Selected Publications and Success Stories.


Featured Publications

Nature Communications, 2026, NEDAMSS syndrome-related truncating and missense mutations are associated with aberrant liquid-liquid phase separation of IRF2BPL

LifeTein synthesized a very long 54 aa peptide spanning the human IRF2BPL HCD core region (a.a. 395–448) with N-terminal acetylation, C-terminal amidation, and purity >95%. The same study also used a 75 aa peptide spanning the ZnF region (a.a. 1–75) with an N-terminal FITC tag linked through a 6-aminohexanoic acid (Ahx) spacer, C-terminal amidation, and purity >90%.

PNAS, Quantitative Structural Assessment of Graded Receptor Agonism

A peptide containing an LXXLL nuclear receptor interaction motif from TRAP220/MED1/DRIP205 was synthesized with an N-terminal FITC label, a six-carbon linker (Ahx), and an amidated C-terminus by LifeTein.

Nature, Monitoring T cell–dendritic cell interactions in vivo by intercellular enzymatic labelling

Biotin–aminohexanoic acid–LPETGS and SELPETGG peptides were purchased from LifeTein, illustrating biotinylated and spacer-modified peptide formats used in advanced biological studies.

Nature Communications, A structural mechanism for directing corepressor-selective inverse agonism of PPARγ

A peptide NCoR1 containing an N-terminal biotin label and an amidated C-terminus for stability was synthesized by LifeTein.

Cell, HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis

The cyclic peptide L50 peptide: Cyclo-(-Arg-Val-Arg-Thr-Arg-Gly-Lys-Arg-Arg-Ile-Arg-Arg-DPro-Pro-) was purchased from LifeTein, illustrating constrained peptide capability.

Nature, EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2

LifeTein designed and synthesized a series of phosphorylated peptides, and the peptides were then used for phospho-specific antibody production.

Cell, A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain

The Wasabi Receptor Toxin, its mutants, biotinylated variants, and Alexa Fluor 488-conjugated variants were synthesized by LifeTein, illustrating advanced labeled peptide capability.

Selected publication examples by capability

These examples are compiled from publicly available literature and are updated periodically. Many additional studies have used LifeTein materials but may not be included in this list.

Related pages

For the broader publication archive, see Selected Publications and Success Stories. For service pages connected to these capabilities, see Long Peptide Synthesis, FITC Peptide Synthesis, and Peptide Synthesis Services.