Human Claudin 18.2 Protein-VLP (LTP10686)
$ 1350 In stock Claudin18(CLDN18) belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells.CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants,CLDN18.1 and CLDN18.2. Isoform 2 (Claudin 18.2) is abundant in gastric tumors.
Full length Human Claudin 18.2 Protein-VLP is expressed from Expi293. It contains Met1-Val261.
The target protein has a predicted MW of 29 kDa.
Immobilized Human Claudin 18.2 VLP at 5ug/ml (100ul/Well). Dose response curve for Anti-Claudin 18.2 Antibody, hFc Tag with the EC50 of 9.8ng/ml determined by ELISA (QC Test). The affinity constant of 2.20 nM as determined in SPR assay (Biacore T200). See testing image for detail.
> 95% as determined by HPLC
Less than 1EU per ug by the LAL method.
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. Notice: If you need it for immunization, Do Not use any adjuvant.
Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Shipped at ambient temperature.
Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.