Product Name | Peptide (TD1-R8), ACSSSPSKHCGGRRRRRRRR, siRNA delivery peptide |
Product Quantity | 5 mg |
Catalog Number | LT12025 |
Molecular Weight | 2367.72 |
Formula | C90H163N47O25S2 |
Sequence | ACSSSPSKHCGGRRRRRRRR, disulfide bridges:C2-C10 |
Purity | >95% |
Product Description | The short synthetic peptide ACSSSPSKHCG (TD1) and oligoarginine (R8) have been shown to facilitate efficient bio-macromolecule delivery through intact skin. The peptide (TD1-R8), ACSSSPSKHCGGRRRRRRRR, can be used to deliver siRNA to the skin. |
Scientific Background | Peptide (TD1-R8), ACSSSPSKHCGGRRRRRRRR, siRNA delivery peptide is a 20-residue synthetic peptide with the sequence Ala-Cys-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys-Gly-Gly-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg. The sequence contains 2 cysteine residues, providing potential thiol/disulfide chemistry when the thiol is available; contains 1 Lys and 8 Arg residues, contributing cationic character. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - thiol-selective conjugation or immobilization studies
- LC-MS/HPLC analytical method development
- sequence-specific assay controls
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Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
