| (Arg)9, Cys C-term, RRRRRRRRRC |
|
The peptide has nine Arginine residues and is modified with an activated cysteine residue C(Npys). The Npys is 3-Nitro-2-pyridinesulfenyl group-protected cysteine. The peptide is used as a carrier peptide in conjugation and cell-permeable studies. The C(Npys) group will react selectively with the free thiol group of any other proteins or antibodies containing a free cysteine. The coupling of sulfhydryls has been studied as an effective means to deliver/release therapeutics such as siRNA in the reducing environment within the cell. It was used for antibody-mediated delivery of siRNAs for anti-HIV therapy. |
|
1mg |
|
>95% |
| LT8113 |
|
1526.84 |
|
C57H115N37O11S |
|
(Arg)9, Cys C-term, RRRRRRRRRC |
|
How to Make Your Peptide Cell Permeable? |
