Cy3-GISYGRKKRRQRRRAHQ

This is a cy3 labeled cell-penetrating peptides (CPPs) derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way. GRKKRRQRRRPPQ; H - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Pro - Pro - Gln - OH

Cy3 Labeled R8 CPP variant Cy3-AAARKKRRQRRRAAA and FAM/TAMRA labeled HIV-1 Tat (48-60) variant:
(5-FAM)-GISYGAKKRRQRRRAHQ-Cys(TAMRA) are available.

Cy3-GISYGRKKRRQRRRAHQ is a 17-residue synthetic peptide with the sequence Gly-Ile-Ser-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Ala-His-Gln. Cy3 provides a fluorescent label for optical detection. The sequence contains 2 Lys and 6 Arg residues, contributing cationic character. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence.

• fluorescence-based detection
• binding or localization assay development
• LC-MS/HPLC analytical method development
• sequence-specific assay controls

Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions.