Cell Permeable Peptides (CPPs)


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Cell Penetrating Peptide Applications

The process of introducing drugs into cells has always proved a major challenge for scientists. However, cell-permeable peptides (CPPs) have the ability to enter the plasma membrane of a cell independent of a membrane receptor. They are usually small peptides 10–30 residues in length with positively charged amino acid sequences.

CPPs are capable of delivering biologically active cargo to the cell interior. The desired therapeutic cargo could be attached to a CPP and then delivered to an intracellular target, thereby overcoming the entry restrictions set by the plasma membrane.

CPPs have gained widespread popularity as very promising non-viral transmembrane delivery vectors. Although they have been used successfully for carrying different cargoes of varying sizes and nature (plasmid DNA, peptides, proteins, nanoparticles, quantum dots, etc.), the most rapid progress has been made with the delivery of oligonucleotides (ONs).

LT12005 Stearyl-R8: Stearyl-RRRRRRRR-NH2   $260     $150,  In Stock
LT8163 LMWP peptide VSRRRRRRGGRRRR $280   In Stock
LT12013 FITC-R8: FITC-Stearyl-RRRRRRRR   $250     $150,  In Stock
LT35796 C(Npys)-(Arg)9: C(Npys)RRRRRRRRR - NH2   $280     $220,  In Stock
LT1615 TAT (47-57): YGRKKRRQRR   $262     $162,  In Stock
LT5549 HIV-1 Tat (48-60): GRKKRRQRRRPPQ   $280     $219,  In Stock

We have a list of in-stock CPPs ready to conjugate with your targets. Your target can be a peptide, protein, fluorescent dye, or nanoparticle. Click for a full list of Cell Permeable Peptides.

Antennapedia Peptide RQIKIWFQNRRMKWKK;
C(Npys)-RQIKIWFQNRRMKWKK;
C-RQIKIWFQNRRMKWKK;
RQIKIWFQNRRMKWKK-C;
In Stock
Penetratin
(GG linker)
RQIKIWFQNRRMKWKK-GG;
C-RQIKIWFQNRRMKWKK-GG;
RQIKIWFQNRRMKWKK-GG-C;
In Stock
Penetratin
and Labeled Antennapedia peptides
RQIRIWFQNRRMRWRR;
C-RQIRIWFQNRRMRWRR;
{FITC-LC}-RQIKIWFQNRRMKWKK;
{5-FAM}-RQIKIWFQNRRMKWKK;
{Cy3}-RQIKIWFQNRRMKWKK;
{Cy5}-RQIKIWFQNRRMKWKK;
{Alexa488}-RQIKIWFQNRRMKWKK;
In Stock
(Arg)9 Oligomer peptides
Fluorescent Labeling
Stearyl-R8;
FITC-Stearyl-R8;
RRRRRRRRRC;
C(Npys)RRRRRRRRR;
HS-cR10: C-(mini-PEG)-(mini-PEG)-KRrRrRrRrRrE;
C(Npys)rrrrrrrrr, r is D amino acid;
{FAM}-RRRRRRRRR;
{TAMRA}-RRRRRRRRR;
{Biotin}-RRRRRRRRR;
{Cy Dyes}-RRRRRRRRR;
{Alexa Dyes}-RRRRRRRRR;
In Stock
TAT (47-57)
and Variants
YGRKKRRQRRR ;
C-YGRKKRRQRRR;
VSRRRRRRGGRRRR;
YGRKKRRQRRR-C;
{Biotin}-YGRKKRRQRRR;
{FAM}-YGRKKRRQRRR;
{TAMRA}-YGRKKRRQRRR;
YGRKKRRQRRRGGGC(Npys);
C(Npys)YGRKKRRQRRR-K(FAM);
MDYKDHDGDYKDHDIDYKDDDDK;
In Stock
TAT GluR23 variants
TAT-NSF222 Fusion Peptide
TAT-NSF700 Fusion Peptide
HIV-1 Tat (48-60)
YGRKKRRQRRR;
YGRKKRRQRRRYKEGYNVYG;
YGRKKRRQRRRVYKYGGYNE;
YGRKKRRQRRRAKEGANVAG;
YGRKKRRQRRR GGG LDKEFNSIFRRAFASRVFPPE;
YGRKKRRQRRR GGG ENSFRFLADIFPAKAFPVRFE;
YGRKKRRQRRR GGG LLDYVPIGPRFSNLVLQALLVL;
YGRKKRRQRRR GGG IPPVYFSRLDLNLVVLLLAQL;
GRKKRRQRRRPPQ;
Cys-GRKKRRQRRRPPQ;
GRKKRRQRRRPPQC;
Cys-GRKKRRQRRR;
RRRQRRKKRGGDIMGEWGNEIFGAIAGFLG;
YGRKKRRQRRRKLSSIESDV;
Crude Peptide In Stock,
HPLC Purify in 5 Days
Cell Permeable-Mastoparan Peptide
NGR peptide, Aminopeptidase N Ligand (CD13)
NGR Peptide 1
Anti-BetaGamma (MPS-Phosducin-like protein C terminus)
Buforin 2
Rabies Virus Glycoprotein (RVG)
Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R)
IKKgamma NEMO Binding Domain (NBD) Inhibitory Peptide
KALA
NF-kB Inhibitor, SN50
pVEC (Cadherin-5)
SV40 Large T-antigen Nuclear Localization Signal (NLS)
SV40 Large T-antigen Nuclear Localization Signal (NLS) derived peptide
TfR Targeting Peptide
Transdermal Peptide
Transportan
Pep-1
Pep-1-Cysteamine
cardiac targeting peptide (CTP)
INLKALAALAKKIL-NH2;
CNGRCG (Disulfide bridge: 1-5);
CNGRCGGklaklakklaklak-NH2 (Disulfide bridge: 1-5);
AAVAL LPAVL LALLA VTDQL GEDFF AVDLE AFLQE FGLLP EKE;
TRSSRAGLQFPVGRVHRLLRK;
YTIWMPENPRPGTPCDIFTNSRGKRASNG;
YTIWM PENPR PGTPC DIFTN SRGKR ASNGG GGRRR RRRRR R;
DRQIKIWFQNRRMKWKKTALDWSWLQTE;
WEAKLAKALAKALAKHLAKALAKALKACEA;
AAVALLPAVLLALLAPVQRKRQKLMP;
LLIILRRRIRKQAHAHSK;
PKKKRKVEDPYC;
CGGGPKKKRKVED;
THRPPMWSPVWP;
ACSSSPSKHCG;
GWTLNSAGYLLGKINLKALAALAKKIL;
KETWWETWWTEWSQPKKKRKV;
Ac-KETWWETWWTEWSQPKKKRKV-cysteamine;
APWHLSSQYSRT
Crude Peptide In Stock,
HPLC Purify in 5 Days
Displaying 11 to 20 (of 30 Products)
Price Product Name-
$280.00 $219.00Save: 22% off... more info
GRKKRRQRRRPPQ
Catalog Number: 5549 Category: Peptide Sequence:HIV TAT (48-60): GRKKRRQRRRPPQ Modifications: This is one of the cell-penetrating peptides (CPPs) derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used...
$380.00... more info
GRKKRRQRRRPPQPVKRRLDL
Catalog Number: 5550 Category: Peptide Sequence: GRKKRRQRRRPPQPVKRRLDL Modifications: Quantity: 4mg Purity: >95 % Notes:
$262.00 $162.00Save: 38% off... more info
HIV-1 tat Protein (47-57)
Product NameHIV-1 tat Protein (47-57)Product Quantity5mg Product Description This is the most characterized fragment of the HIV transactivator protein (TAT) YGRKKRRQRR. This arginine-rich TAT peptide penetrates plasma membrane directly, but not...
$262.00... more info
HIV-1 tat Protein Cys TAT (47-57)
Product Name HIV-1 tat Protein Cys TAT (47-57)Product Quantity5mg Product Description This is the most characterized fragment of the HIV transactivator protein (TAT) CYGRKKRRQRR. This arginine-rich TAT peptide penetrates plasma membrane directly,...
$890.00... more info
HS-cR10
Product Name HS-cR10 Product Quantity 5 mg Purity >95% Catalog Number LT8154 Molecular Weight C86H168N47O20S [M + H]+, 2213; [M + 2H]2+,1107; found, 1108 Formula C86H168N47O20S Sequence C-(mini-PEG)-(mini-PEG)-KRrRrRrRrRrE, C-Terminal:...
$280.00... more info
LMWP peptide VSRRRRRRGGRRRR
Catalog Number: LT8163 Category: Peptide Sequence:Low Molecular Weight Protamine (LMWP): VSRRRRRRGGRRRR Modifications: Low Molecular Weight Protamine (LMWP), with the sequence VSRRRRRRGGRRRR, is a peptide derived from protamine, a naturally...
$99.00... more info
Penetratin
Product Name Penetratin Catalog #LT8103 Quantity1mg Purity >98% Price $ 99 In stock SequenceRQIKIWFQNRRMKWKKGG, Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Gly-Gly DescriptionThe DNA binding domain of the...
$99.00... more info
Penetratin, Cys C-term
Product Name Penetratin, Cys C-term Catalog #LT8105 Quantity1mg Purity >98% Price $ 99 In stock SequenceRQIKIWFQNRRMKWKKGGC, Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Gly-Gly-Cys DescriptionThe DNA binding...
$99.00... more info
Penetratin, Cys N-term
Product Name Penetratin, Cys N-term Catalog #LT8104 Quantity1mg Purity >98% Price $ 99 In stock SequenceCRQIKIWFQNRRMKWKKGG, Cys-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Gly-Gly DescriptionThe DNA binding...
$99.00... more info
Penetratin-Arg
Product Name Penetratin-Arg Catalog #LT8106 Quantity1mg Purity >98% Price $ 99 In stock SequenceRQIRIWFQNRRMRWRR, Arg - Gln - Ile - Arg - Ile - Trp - Phe - Gln - Asn - Arg - Arg - Met - Arg - Trp - Arg - Arg DescriptionThe DNA...
Displaying 11 to 20 (of 30 Products)
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