Cell Permeable Peptides (CPPs)

Peptide synthesis: Cell permeable Peptide Anti-Cancer

The process of introducing drugs into cells has always proved a major challenge for scientists. However, cell-permeable peptides (CPPs) have the ability to enter the plasma membrane of a cell independent of a membrane receptor. They are usually small peptides 10–30 residues in length with positively charged amino acid sequences.

CPPs are capable of delivering biologically active cargo to the cell interior. The desired therapeutic cargo could be attached to a CPP and then delivered to an intracellular target, thereby overcoming the entry restrictions set by the plasma membrane.

CPPs have gained widespread popularity as very promising non-viral transmembrane delivery vectors. Although they have been used successfully for carrying different cargoes of varying sizes and nature (plasmid DNA, peptides, proteins, nanoparticles, quantum dots, etc.), the most rapid progress has been made with the delivery of oligonucleotides (ONs).

LT12005 Stearyl-RRRRRRRR-NH2   $260     $150,  In Stock
LT12013 FITC-Stearyl-RRRRRRRR   $250     $150,  In Stock
LT35796 C(Npys)RRRRRRRRR - NH2   $280     $220,  In Stock
LT1615 YGRKKRRQRR   $262     $162,  In Stock
LT5549 GRKKRRQRRRPPQ   $280     $219,  In Stock

We have a list of in-stock CPPs ready to conjugate with your targets. Your target can be a peptide, protein, fluorescent dye, or nanoparticle. Click for a full list of Cell Permeable Peptides.

LT8100 RQIKIWFQNRRMKWKK;
C(Npys)-RQIKIWFQNRRMKWKK;
C-RQIKIWFQNRRMKWKK;
RQIKIWFQNRRMKWKK-C;
98mg crude, In Stock
LT8103
(GG linker)
RQIKIWFQNRRMKWKK-GG;
C-RQIKIWFQNRRMKWKK-GG;
RQIKIWFQNRRMKWKK-GG-C;
80mg crude, In Stock
LT8106 RQIRIWFQNRRMRWRR;
C-RQIRIWFQNRRMRWRR;
{FITC-LC}-RQIKIWFQNRRMKWKK;
{5-FAM}-RQIKIWFQNRRMKWKK;
{Cy3}-RQIKIWFQNRRMKWKK;
{Cy5}-RQIKIWFQNRRMKWKK;
{Alexa488}-RQIKIWFQNRRMKWKK;
50mg crude; In Stock
LT8109 RRRRRRRRR;
C(Npys)RRRRRRRRR;
C(Npys)rrrrrrrrr, r is D amino acid;
{FAM}-RRRRRRRRR
{TAMRA}-RRRRRRRRR
{Biotin}-RRRRRRRRR
{Cy Dyes}-RRRRRRRRR
{Alexa Dyes}-RRRRRRRRR
100mg crude; In Stock
LT8114 YGRKKRRQRRR; C-YGRKKRRQRRR;
YGRKKRRQRRR-C;
{Biotin}-YGRKKRRQRRR;
{FAM}-YGRKKRRQRRR;
{TAMRA}-YGRKKRRQRRR;
YGRKKRRQRRRGGGC(Npys);
C(Npys)YGRKKRRQRRR-K(FAM);
MDYKDHDGDYKDHDIDYKDDDDK;
60mg; In Stock
LT8123-LT8152 YGRKKRRQRRR; YGRKKRRQRRRYKEGYNVYG;
YGRKKRRQRRRVYKYGGYNE;
YGRKKRRQRRRAKEGANVAG;
YGRKKRRQRRR-GGG-LDKEFNSIFRRAFASRVFPPE;
YGRKKRRQRRR-GGG-ENSFRFLADIFPAKAFPVRFE;
YGRKKRRQRRR-GGG-LLDYVPIGPRFSNLVLQALLVL;
YGRKKRRQRRRGGGIPPVYFSRLDLNLVVLLLAQL;
GRKKRRQRRRPPQ;
Cys-GRKKRRQRRRPPQ;
GRKKRRQRRRPPQC;
Cys-GRKKRRQRRR;
RRRQRRKKRGGDIMGEWGNEIFGAIAGFLG;
YGRKKRRQRRRKLSSIESDV;
INLKALAALAKKIL;
[CNGRC]G;
[CNGRC]GGklaklakklaklak;
AAVALL PAVLL ALLAV TDQLG EDFFA VDLEA FLQEF GLLPE KE;
TRSSRAGLQFPVGRVHRLLRK;
YTIWMPENPRPGTPCDIFTNSRGKRASNG;
YTIWMPENPRPGTPCDIFTNSRGKRASNG GGG RRRRRRRRR;
DRQIKIWFQNRRMKWKKTALDWSWLQTE;
WEAKLAKALAKALAKHLAKALAKALKACEA;
AAVALLPAVLLALLAPVQRKRQKLMP;
LLIILRRRIRKQAHAHSK;
PKKKRKVEDPYC;
CGGGPKKKRKVED;
THRPPMWSPVWP;
ACSSSPSKHCG;
GWTLNSAGYLLGKINLKALAALAKKIL;
KETWWETWWTEWSQPKKKRKV;
Ac-KETWWETWWTEWSQPKKKRKV;
Quantity Varies; In Stock
Displaying 1 to 10 (of 14 Products)
Price+ Product Name
$300.00 $150.00Save: 50% off... more info
FITC-Stearyl-R8
Product Name FITC-Stearyl-R8 Product Quantity 1mg Purity 95.89% Catalog Number LT12013 Molecular Weight 2107.64 Formula C95H159N37O16S Sequence CH3(CH2)16-CONH-RRRRRRRRGK(FITC)-NH2 Description Polyarginine peptides, which are very...
$312.00 $150.00Save: 52% off... more info
Stearyl-R8
Product Name Stearyl-R8 Product Quantity 5 mg Purity >95% Catalog Number LT12005 Molecular Weight 1533.01 Formula C66H133N33O9 Sequence Stearyl-RRRRRRRR-NH2 Description Polyarginine peptides, which are very efficient CPPs have been used...
$312.00 $150.00Save: 52% off... more info
Stearyl-R8
Product Name Stearyl-R8 Product Quantity 5mg Purity >95% Catalog Number LT12005 Molecular Weight 1533.01 Formula C66H133N33O9 Sequence Stearyl-RRRRRRRR-NH2 Description Polyarginine peptides, which are very efficient CPPs have been used...
$420.00 $189.00Save: 55% off... more info
Transdermal Peptide TD1, ACSSSPSKHCG, acetylated, amidated
Product Name Transdermal Peptide TD1, ACSSSPSKHCG, acetylated, amidated, acetate salt Product Description The short synthetic peptide ACSSSPSKHCG (TD1) and oligoarginine (R8) have been shown to facilitate efficient bio-macromolecule delivery...
$336.00 $220.00Save: 35% off... more info
Cys(Npys)-(Arg)9: C(Npys)RRRRRRRRR-NH2
Product NameCys(Npys)-(Arg)9: C(Npys)RRRRRRRRR - NH2Product Description The peptide has nine Arginine residues and is modified with an activated cysteine residue C(Npys). The Npys is 3-Nitro-2-pyridinesulfenyl group protected cysteine. The peptide...
$280.00... more info
GRKKRRQRRRPPQ
Catalog Number: 5549 Category: Peptide Sequence:HIV TAT (48-60): GRKKRRQRRRPPQ Modifications: This is one of the cell-penetrating peptides (CPPs) derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used...
$280.00... more info
RQIKIWFQNRRMKWKKGGHHHHHH
Catalog Number: 6206 Category: Peptide Sequence: RQIKIWFQNR RMKWKKGGHH HHHH; NH2- Arg - Gln - Ile - Lys - Ile - Trp - Phe - Gln - Asn - Arg - Arg - Met - Lys - Trp - Lys - Lys - Gly - Gly - His - His - His - His - His - His -COOH ...
$350.00... more info
RQIKIWFQNR RMKWKKGLSM MRALHNFLTA GVPAEG
Catalog Number: 5591 Category: Peptide Sequence: RQIKIWFQNR RMKWKKGLSM MRALHNFLTA GVPAEG; NH2- Arg - Gln - Ile - Lys - Ile - Trp - Phe - Gln - Asn - Arg - Arg - Met - Lys - Trp - Lys - Lys - Gly - Leu - Ser - Met - Met - Arg - Ala - Leu - His -...
$380.00... more info
GRKKRRQRRRPPQPVKRRLDL
Catalog Number: 5550 Category: Peptide Sequence: GRKKRRQRRRPPQPVKRRLDL Modifications: Quantity: 4mg Purity: >95 % Notes:
$380.00... more info
RQIKIWFQNR RMKWKKGGGW DTEIKDDVIE ECNKHGGVHH HHHH
Catalog Number: 6207 Category: Peptide Sequence: RQIKIWFQNR RMKWKKGGGW DTEIKDDVIE ECNKHGGVHH HHHH; NH2- Arg - Gln - Ile - Lys - Ile - Trp - Phe - Gln - Asn - Arg - Arg - Met - Lys - Trp - Lys - Lys - Gly - Gly - Gly - Trp - Asp - Thr - Glu -...
Displaying 1 to 10 (of 14 Products)
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