HIV-1 tat Protein Cys-TAT (47-57), Cys-TAT Cys N-term

Product Name
HIV-1 tat Protein Cys-TAT (47-57), Cys-TAT Cys N-term
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Product Description

This is the most characterized fragment of the HIV transactivator protein (TAT) YGRKKRRQRRR. This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis. Oligomers of the TAT(47-57) peptide compact plasmid DNA to nanometric particles and stabilize DNA towards nuclease degradation. At optimized vector compositions. these peptides mediated gene delivery to cells in culture 6-8-fold more efficiently than poly-L-arginine or the mutant TAT2-M1. The HIV-tat peptide YGRKKRRQRRR is a powerful tool in biotechnology and medicine, primarily due to its cell-penetrating capabilities. Its applications range from genetic engineering in microalgae to enhancing drug delivery and protecting against UV-induced skin damage. The ongoing research into its uptake mechanisms and potential uses in various fields highlights its versatility and importance in scientific advancements.

Catalog Number
Molecular Weight
Cys-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2, CYGRKKRRQRRR, amide
  • 2 Units in Stock

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