Obesity Treatment: A New Peptide Drug

Targeted Drug Melts Fat in Obese Monkeys Currently, only two Food and Drug Administration (FDA) approved drugs for weight loss are available in the United States: the appetite suppressant phentermine and the inhibitor of fat absorption orlistat.

Peptide Drug for Obesity

An MD Anderson group designed a new peptide drug: CKGGRAKDC-GG-D(KLAKLAK)2 (adipotide). This is a synthetic peptide that triggers cell death. These data showed that the peptide might be helpful in treating obesity in humans. The MD Anderson group used a peptide library to screen and identify regions that bind to specific vascular cells. The interaction identified will be used as effective drugs to target particular protein functions. This video explains factors that have contributed to the obesity epidemic.

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Synthetic Peptide Vaccine Research: Problems and Accomplishments

Immune-based cancer treatments are one emerging type of therapy, and they show great potential. Synthetic-peptide-based vaccines, which are designed to elicit T cell immunity, are also a promising approach to the prevention and treatment of both infectious diseases and malignant disorders, such as cancer.

Research on Synthetic Peptide Vaccines

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Amino acid composition of cell-penetrating peptides (CPPs)

Obesity Treatment: A New Peptide Drug

Peptide Synthesis for Cell-penetration Studies

D-amino acid peptides to resist common proteases