Peptide protein binding strategies: Structure, Volume 18, Issue 2, 188-199, 10 February 2010
Peptide-Protein Binding
Highlights
- After binding its partners, most peptides do not introduce any conformational changes
- The interfaces of peptide-protein have more hydrogen bonds
- The peptide hotspots are important for the binding
- Peptides prefer to bind in the largest pockets on the protein surface
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