Human Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (LTP10163)

Product Name
Human Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (LTP10163)
Catalog Number
LTP10163
Quantity
100ug
Price
$563 In stock
Background
The ?2?1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins. It is now recognized that the ?2?1 integrin serves as a receptor for many matrix and nonmatrix molecules. It plays a critical role in platelet function and homeostasis.
Description
Recombinant Human Integrin alpha 2 beta 1(ITGA2&ITGB1) Heterodimer Protein is expressed from Expi293 with His tag at the C-terminal. It contains Tyr30-T1132(ITGA2)&Gln21-Asp728(ITGB1).
Target
Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer
Species
Human
Gene/Protein ID
P17301-1(ITGA2)&P05556(ITGB1)
Exact Sequence
Tyr30-T1132(ITGA2) & Gln21-Asp728(ITGB1)
Molecular Weight
The protein has a predicted MW of 126.6 kDa(ITGA2)&83.2 kDa(ITGB1). Due to glycosylation, the protein migrates to 110-140 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-His
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Human Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (LTP10163)
  • 5 Units in Stock
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