Catalog Number | LT8876 |
Product Name | TAT-NSF222scr Scrambled Control Peptide |
Product Quantity | 1 mg |
Sequence | YGRKKRRQRRR-GGG-ENSFRFLADIFPAKAFPVRFE |
Molecular Weight | 4215.1 |
Purity | ≥95% |
Scientific Background | TAT-NSF222scr is a scrambled-sequence control for the TAT-NSF222 fusion peptide. It retains the HIV TAT(47-57) cell-penetrating domain and Gly3 linker while scrambling the NSF-derived D1-domain sequence. The control was developed to help distinguish sequence-dependent inhibition of NSF and regulated exocytosis from nonspecific effects of peptide delivery or the TAT segment. |
Research Applications | - TAT-NSF222 control experiments
- NSF ATPase studies
- SNARE and exocytosis research
- cell-penetrating peptide controls
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Experimental Notes | TAT-NSF222scr is intended as a matched sequence control and should be used under conditions parallel to the active TAT-NSF222 peptide. Scrambling does not justify assuming absence of every possible biological effect in all systems. |
Selected References | - A Novel Class of Fusion Polypeptides Inhibits Exocytosis
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