Neutrophil Elastase Substrate, MeOSuc-AAPV-pNA

MeOSuc-AAPV-pNA is a chromogenic substrate widely used for human neutrophil elastase. Cleavage after the AAPV recognition sequence releases p-nitroaniline for absorbance-based enzyme assays.

• protease activity assays
• MMP or serine-protease research
• coagulation and fibrinolysis studies
• enzyme inhibitor screening

Fluorophore, quencher, chromophore and terminal blocking groups are integral to exact reagent identity. Detection wavelengths and enzyme selectivity should be validated for each assay system.

1. Selected peer-reviewed publication