Histone H3 (1-25), amide

Histone H3(1-25)-NH2 contains the major N-terminal regulatory sites Lys4, Lys9, Lys14, Lys18 and Lys23 in an amidated sequence context. It is useful as an unmodified reference for enzyme and chromatin-reader studies.

• histone methylation studies
• chromatin enzyme assays
• epigenetic reader studies
• modification-state controls

The exact fragment boundaries, methylation state and terminal chemistry are part of the reagent identity. Use sequence-matched controls for modification-dependent comparisons.

1. Selected publication