Histone H3 (1-21) K9Ac/K14Ac-GGK(Biotin)

This doubly acetylated H3 tail contains both K9ac and K14ac, modeling a combinatorial active-chromatin state. Multi-acetylated peptides are useful for studying reader avidity and modification crosstalk that cannot be captured by single-site substrates alone.

• multi-acetyl histone binding
• bromodomain profiling
• chromatin reader studies
• epigenetic assay development

Dual acetylation changes both charge and reader recognition relative to the individual K9Ac and K14Ac peptides. The product should remain a separate exact-form entry.

1. Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation