Catalog Number | LT9017 |
| Product Name | Histone H3 (1-21) K9Ac-GGK(Biotin)-NH2 |
| Product Quantity | 1 mg |
| Sequence | ARTKQTAR-K(Ac)-STGGKAPRKQLA-GGK(Biotin)-NH2 |
| Molecular Weight | 2764.4 |
| Formula | |
| Purity | ≥95% |
| Scientific Background | H3K9ac is strongly associated with transcriptionally active chromatin and is enriched near transcription start sites. This biotinylated H3K9ac peptide provides a defined ligand for acetyl-lysine reader proteins and for biochemical studies of modification-dependent chromatin interactions. |
| Research Applications | - bromodomain binding assays
- H3K9 acetylation research
- chromatin protein pull-downs
- epigenetic reader screening
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| Experimental Notes | The C-terminal GGK-biotin handle and amide are part of the exact reagent. H3K9ac has different biological and biochemical recognition properties from H3K9 methylated forms. |
| Selected References | - Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome
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