Histone H3 (1-10) K4Me3

H3K4me3 is strongly associated with active transcription start sites and is recognized by multiple PHD-finger and other methyl-lysine reader proteins. The H3(1-10) fragment provides a minimal trimethyl-Lys4 ligand.

• histone methylation studies
• chromatin enzyme assays
• epigenetic reader studies
• modification-state controls

The exact fragment boundaries, methylation state and terminal chemistry are part of the reagent identity. Use sequence-matched controls for modification-dependent comparisons.

1. Selected publication