[Gly22]-Beta-Amyloid (1-40), Arctic Mutation

The E22G Arctic mutation promotes formation of soluble Aβ assemblies and is widely used to investigate mutation-dependent aggregation, protofibril formation and amyloid toxicity.

• familial amyloid mutation studies
• Aβ aggregation and oligomerization
• Alzheimer disease research
• mutant versus wild-type comparisons

Mutation identity and Aβ C-terminal length are integral to this reagent. Compare with the sequence-matched wild-type Aβ40 or Aβ42 under identical preparation and aggregation conditions.

1. Selected mutation/amyloid study