[Gly21]-Beta-Amyloid (1-40), A21G Flemish Mutation

Catalog Number
LT9146
Product Name[Gly21]-Beta-Amyloid (1-40), A21G Flemish Mutation
Product Quantity0.5 mg
SequenceDAEFRHDSGYEVHHQKLVFFGEDVGSNKGAIIGLMVGGVV
MutationA21G
Molecular Weight4316.1
Purity≥95%
Scientific Background

The A21G Flemish variant is associated with familial amyloid disease and has distinct aggregation and vascular-deposition behavior. This Aβ40 form is useful for mutation-dependent assembly comparisons.

Research Applications
  • familial amyloid mutation studies
  • Aβ aggregation and oligomerization
  • Alzheimer disease research
  • mutant versus wild-type comparisons
Experimental Notes

Mutation identity and Aβ C-terminal length are integral to this reagent. Compare with the sequence-matched wild-type Aβ40 or Aβ42 under identical preparation and aggregation conditions.

Selected References
  1. Selected mutation/amyloid study
  • 1 Units in Stock
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