[Gly14]-Humanin (HNG)

The S14G Humanin analog, commonly called HNG, is a potent Humanin derivative used in studies of neuronal survival, amyloid-beta toxicity and metabolic signaling. The Ser-to-Gly substitution can markedly enhance biological activity.

• neuroscience and neuroprotection research
• neuropeptide receptor pharmacology
• cell-signaling studies
• neuroendocrine and metabolic research

Sequence length, species, terminal chemistry and analog substitutions define the exact reagent. Use sequence-matched controls and consistent preparation conditions.

1. Selected peer-reviewed publication