[Gly21]-Beta-Amyloid (1-42), Flemish Mutation

Catalog Number
LT9182
Product Name[Gly21]-Beta-Amyloid (1-42), Flemish Mutation
Product Quantity0.5 mg
SequenceDAEFRHDSGYEVHHQKLVFFGEDVGSNKGAIIGLMVGGVVIA
MutationA21G
Molecular WeightTBD
Purity≥95%
Scientific Background

The A21G Flemish mutation is associated with familial amyloid disease and changes Aβ assembly and vascular deposition. This Aβ42 form allows direct comparison with the corresponding Aβ40 mutant.

Research Applications
  • familial Aβ mutation studies
  • amyloid aggregation and oligomerization
  • cerebral amyloid angiopathy research
  • mutant versus wild-type comparisons
Experimental Notes

Mutation identity and Aβ length define this reagent. Compare with sequence-matched wild-type Aβ42 or the corresponding Aβ40 mutant under identical preparation conditions.

Selected References
  1. Selected familial amyloid mutation publication
  • 1 Units in Stock
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