Caspase-8 Inhibitor, Ac-IETD-CHO

Ac-IETD-CHO is a peptide aldehyde inhibitor based on a preferred caspase-8 recognition motif and is used to investigate death-receptor and initiator-caspase pathways.

• caspase and apoptosis research
• protease activity assays
• inflammasome or cytotoxicity studies
• enzyme inhibitor profiling

Reporter group and terminal warhead are integral to reagent identity. AMC and pNA substrates require different detection modes, while aldehyde derivatives are inhibitors rather than turnover substrates.

1. Selected peer-reviewed publication