Caspase-3 Inhibitor, Ac-DEVD-CHO

Ac-DEVD-CHO is a reversible aldehyde inhibitor built from the DEVD recognition motif of executioner caspases. It is used to suppress caspase-3-like activity in biochemical and apoptosis studies.

• caspase and apoptosis research
• protease activity assays
• inflammasome or cytotoxicity studies
• enzyme inhibitor profiling

Reporter group and terminal warhead are integral to reagent identity. AMC and pNA substrates require different detection modes, while aldehyde derivatives are inhibitors rather than turnover substrates.

1. Selected peer-reviewed publication