[Asn23]-Beta-Amyloid (1-40), Iowa Mutation

The D23N Iowa mutation alters a charged residue in the central Aβ turn region and is associated with hereditary cerebral amyloid angiopathy. This Aβ40 reagent supports mutation-dependent aggregation and vascular amyloid studies.

• familial Aβ mutation studies
• amyloid aggregation and oligomerization
• cerebral amyloid angiopathy research
• mutant versus wild-type comparisons

Mutation identity and Aβ length define this reagent. Compare with sequence-matched wild-type Aβ42 or the corresponding Aβ40 mutant under identical preparation conditions.

1. Selected familial amyloid mutation publication