[Asn23]-Beta-Amyloid (1-42), Iowa Mutation

The D23N Iowa mutation in the Aβ42 background combines the familial central-region substitution with the aggregation-prone 42-residue C terminus, providing a defined comparator for wild-type Aβ42.

• familial Aβ mutation studies
• amyloid aggregation and oligomerization
• cerebral amyloid angiopathy research
• mutant versus wild-type comparisons

Mutation identity and Aβ length define this reagent. Compare with sequence-matched wild-type Aβ42 or the corresponding Aβ40 mutant under identical preparation conditions.

1. Selected familial amyloid mutation publication