Amylin, Human

Human amylin, or islet amyloid polypeptide, is a 37-residue amidated hormone co-secreted with insulin. It regulates gastric emptying and satiety and is also strongly amyloidogenic, making it important in type 2 diabetes and aggregation research.

• calcitonin-family receptor pharmacology
• cardiovascular or metabolic signaling
• bone and calcium-homeostasis studies
• amyloid and aggregation research

N-terminal disulfide loops, C-terminal amidation, species sequence and analog substitutions are part of the exact molecular identity and can substantially change receptor activity or aggregation behavior.

1. Selected peer-reviewed publication