Amylin (8-37), Human

Human amylin(8-37) lacks the N-terminal disulfide loop and functions as an amylin-receptor antagonist in many experimental systems. It is used to distinguish receptor-mediated actions of intact amylin.

• calcitonin-family receptor pharmacology
• cardiovascular or metabolic signaling
• bone and calcium-homeostasis studies
• amyloid and aggregation research

N-terminal disulfide loops, C-terminal amidation, species sequence and analog substitutions are part of the exact molecular identity and can substantially change receptor activity or aggregation behavior.

1. Selected peer-reviewed publication