Amylin, Rat

Rat amylin is a species-specific 37-residue amidated peptide with sequence substitutions that make it substantially less amyloidogenic than human amylin. It is valuable for comparative aggregation, receptor and metabolic studies.

• calcitonin-family receptor pharmacology
• cardiovascular or metabolic signaling
• bone and calcium-homeostasis studies
• amyloid and aggregation research

N-terminal disulfide loops, C-terminal amidation, species sequence and analog substitutions are part of the exact molecular identity and can substantially change receptor activity or aggregation behavior.

1. Selected peer-reviewed publication