Catalog Number | LT8874 |
Product Name | TAT-NSF700scr Scrambled Control Peptide |
Product Quantity | 1 mg |
Sequence | YGRKKRRQRRR-GGG-IPPVYFSRLDLNLVVLLLAQL |
Molecular Weight | 4110.2 |
Formula | C186H315N61O44 |
Purity | ≥95% |
Scientific Background | TAT-NSF700scr is a cell-permeable scrambled control peptide for the TAT-NSF700 experimental system. It combines the HIV TAT(47-57) protein-transduction sequence with a Gly3 linker and a scrambled NSF-derived segment. Published studies use TAT-NSF700scr as a matched control when investigating NSF-dependent SNARE-complex disassembly and regulated exocytosis, while the active TAT-NSF700 peptide inhibits NSF function. |
Research Applications | - TAT-NSF700 control experiments
- NSF and SNARE exocytosis studies
- endothelial secretion research
- cell-penetrating peptide controls
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Experimental Notes | A scrambled peptide is a matched experimental control, not a guarantee of universal biological inactivity. It should be tested at the same concentration and under the same exposure conditions as TAT-NSF700. |
Selected References | - A Novel Inhibitor of N-Ethylmaleimide-Sensitive Factor Decreases Leukocyte Trafficking and Peritonitis
- A Novel Class of Fusion Polypeptides Inhibits Exocytosis
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