Substance P (1-7)

Substance P(1-7) is an N-terminal metabolite of Substance P with biological activities that differ from the parent tachykinin. It has been studied in pain modulation, opioid-related behavior and neuroimmune signaling.

• neuropeptide receptor pharmacology
• GPCR signaling
• neuroendocrine and smooth-muscle studies
• structure-activity research

Terminal pyroglutamate, amidation and exact residue boundaries are part of the reagent identity and should be retained when comparing tachykinin or bombesin-family activity.

1. Selected peer-reviewed publication