Srctide Multi-Kinase Substrate

Catalog Number
LT8902
Product Name
Srctide Multi-Kinase Substrate
Product Quantity
1 mg
Sequence
GEEPLYWSFPAKKK-NH2
Molecular Weight
1679.0
Formula
C81H119N19O20
Purity
≥95%
Scientific Background

Srctide, GEEPLYWSFPAKKK-NH2, is a synthetic tyrosine-containing kinase substrate used with Src and a broad range of receptor and non-receptor protein tyrosine kinases. The tyrosine residue provides the principal phosphorylation site, and the C-terminal amide defines this chemical form. Its broad kinase compatibility makes Srctide useful for comparative enzyme assays and screening workflows rather than as an exclusively Src-specific reporter.

Research Applications
  • protein tyrosine kinase activity assays
  • Src-family and receptor tyrosine kinase studies
  • kinase inhibitor screening
  • comparative substrate profiling
Experimental Notes

Srctide can be phosphorylated by multiple kinases, so activity in mixed biological samples cannot be assigned to Src alone without selective inhibitors, immunopurification or other orthogonal controls.

Selected References
  1. ATI-1777, a Topical Jak1/3 Inhibitor, May Benefit Atopic Dermatitis without Systemic Drug Exposure
  • 1 Units in Stock
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