[Pyr3]-Beta-Amyloid (3-40)

Pyroglutamate Aβ(3-40) lacks Asp1-Ala2 and contains cyclized Glu3. Pyroglutamate Aβ species are important components of amyloid heterogeneity and are studied for altered stability, aggregation and clearance.

• amyloid-beta aggregation research
• Alzheimer disease research
• sequence and truncation comparisons
• biochemical assay development

Exact fragment boundaries, sequence orientation and labeling chemistry define this reagent. Use matched wild-type or unlabeled controls under identical preparation conditions.

1. Selected amyloid-beta publication