PLP (139-151)

PLP(139-151) is one of the best-characterized encephalitogenic epitopes in experimental autoimmune encephalomyelitis, particularly in SJL mice. It is a standard peptide antigen for studies of myelin-reactive T cells, demyelination and relapse.

• experimental autoimmune encephalomyelitis / neuritis
• multiple-sclerosis and demyelination research
• myelin epitope mapping
• T-cell and antibody recognition studies

Species assignment, residue boundaries, substitutions, terminal caps and affinity labels are part of the exact reagent identity. Use the matching species/epitope form when reproducing published autoimmune-myelin models.

1. Selected peer-reviewed myelin/autoimmunity study