| Palmitoyl Pentapeptide‑4, often known by its commercial name Matrixyl, is a cutting-edge signal peptide used extensively in anti-aging skincare formulations. Its structure features a short amino acid sequence (KTTKS: Lys‑Thr‑Thr‑Lys‑Ser) tethered to a 16-carbon palmitic acid chain, which significantly enhances its ability to penetrate the lipid-rich skin barrier.
Palmitoyl Pentapeptide‑4 (Matrixyl) is a scientifically validated signal peptide that revitalizes skin by stimulating collagen and fibronectin synthesis. Its palmitoyl lipid chain ensures deep skin penetration, delivering anti-aging benefits at ultra-low concentrations. Clinically proven to reduce fine lines and boost skin elasticity-often matching retinol's efficacy but with superior tolerability. Recognized for safety in cosmetic applications, it's the gold standard for luxurious, effective skincare. Acts as a matrikine, mimicking the body’s natural extracellular matrix signaling. It stimulates fibroblasts to boost the production of collagen types I, II, III, and fibronectin, key proteins for skin structure and resilience.
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