Catalog Number | LT8988 |
Product Name | OVA (323-339), FITC-LC-Labeled |
Product Quantity | 1 mg |
Sequence | FITC-LC-ISQAVHAAHAEINEAGR |
Molecular Weight | 2276.6 |
Purity | ≥95% |
Scientific Background | FITC-LC-ISQAVHAAHAEINEAGR is a fluorescent OVA(323-339) MHC class II peptide carrying a long-chain spacer between FITC and the epitope. The fluorescent reporter enables peptide uptake, localization and antigen-handling studies while the spacer reduces direct steric contact between FITC and the peptide sequence. |
Research Applications | - MHC class II antigen processing
- CD4 T-cell immunology
- fluorescent peptide uptake
- antigen-presentation imaging
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Experimental Notes | FITC-LC labeling creates a distinct reagent from TAMRA- or biotinylated OVA(323-339). Fluorophore attachment can alter uptake and MHC loading, so functional assays should include the unlabeled peptide. |
Selected References | - DNA Vaccines, Combining Form of Antigen and Method of Delivery to Raise a Spectrum of IFN-γ and IL-4-Producing CD4+ and CD8+ T Cells
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