Orexin A, Bovine/Human/Mouse/Rat

Orexin A is a hypothalamic neuropeptide acting at OX1R and OX2R receptors. It regulates arousal, sleep-wake state, feeding, energy homeostasis and autonomic signaling. Its two intramolecular disulfide bridges are essential parts of the native folded peptide.

• neuropeptide receptor pharmacology
• GPCR and cell-signaling research
• neuroscience and behavioral studies
• peptide structure-activity analysis

Species, terminal amidation, D-amino-acid configuration, disulfide connectivity and affinity labels are part of the exact reagent identity and should be preserved when comparing published assays.

1. Selected peer-reviewed publication