Product Name | NLVPMVATV CMV pp65 (495 - 503) |
Product Quantity | 5 mg, >97% Purity by HPLC |
Catalog Number | LT-1778 |
Molecular Weight | 942.80 |
Formula | C42H74N10S1O12 |
Sequence | NLVPMVATV, H-Asn-Leu-Val-Pro-Met-Val-Ala-Thr-Val-OH |
Product Description | Antigen Peptide CMV pp65 is HLA-A*0201-restricted epitope from Cytomegalovirus pp65 (495-503). Human cytomegalovirus (CMV) is a species of the Cytomegalovirus genus of viruses. It is also known as human herpesvirus-5 (HHV-5). CMV pp65 (ppUL83) is the major constituent of both virions and noninfectious particles called dense bodies. They are localized predominantly to the nucleus after virus penetration and accumulates in both nucleus and cytoplasm as virus matures late in infection. The peptide NLVPMVATV can stimulate human CMV-specific CD8+ T-cells. |
Scientific Background | NLVPMVATV CMV pp65 (495 - 503) is a 9-residue synthetic peptide with the sequence Asn-Leu-Val-Pro-Met-Val-Ala-Thr-Val. The sequence has a relatively high hydrophobic-residue fraction that can influence aqueous solubility and surface adsorption. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
