Product Name | NLVPMVATV |
Product Quantity | 4mg |
Catalog Number | LT8257 |
Category | CMV_pp65 |
Sequence | NLVPMVATV |
Purity | >95% |
Product Description | The NLVPMVATV peptide is a well-characterized epitope derived from the pp65 protein of human cytomegalovirus (HCMV). This peptide is presented by HLA-A*02:01 molecules and is recognized by CD8+ cytotoxic T lymphocytes (CTLs). Due to its immunodominance, NLVPMVATV is widely used in immunological studies to monitor CMV-specific T-cell responses, especially in immunocompromised individuals such as transplant recipients. Its consistent recognition across different individuals makes it a valuable tool in vaccine development and adoptive T-cell therapies. |
Scientific Background | NLVPMVATV is a 9-residue synthetic peptide with the sequence Asn-Leu-Val-Pro-Met-Val-Ala-Thr-Val. The sequence has a relatively high hydrophobic-residue fraction that can influence aqueous solubility and surface adsorption. These sequence-derived properties describe the reagent chemically; no specific receptor, enzyme, pathway, disease association, or biological activity is assigned without product-specific experimental evidence. |
Research Applications | - LC-MS/HPLC analytical method development
- sequence-specific assay controls
|
Experimental Notes | Sequence-derived chemical properties support reagent selection and experimental planning but do not establish biological function. Solubility, aggregation, adsorption, conjugation efficiency, and assay performance should be validated under the intended experimental conditions. |
