Mouse PILRA Protein (LTP10317)

Product Name
Mouse PILRA Protein (LTP10317)
Catalog Number
LTP10317
Quantity
100ug
Price
$406 In stock
Background
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.
Description
Recombinant Mouse PILRA Protein is expressed from Expi293 with hFc tag at the C-terminal. It contains Glu32-Val197.
Target
PILRA
Species
Mouse
Gene/Protein ID
Q2YFS3-1
Exact Sequence
Glu32-Val197
Molecular Weight
The protein has a predicted MW of 45.4 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on the Tris-Bis PAGE result.
Activity
0
Tag
C-hFc
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

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Mouse PILRA Protein (LTP10317)
  • 5 Units in Stock
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