|  | Mouse CDH17/Cadherin 17 Protein (LTP10486) | 
    
    |  | LTP10486 | 
    
    |  | 100ug | 
    
    |  | 
    $450 In stock | 
 |  | Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. | 
|  | Recombinant Mouse CDH17/Cadherin 17 Protein is expressed from Expi293 with His tag at the C-terminal. It contains Phe26-Met786. | 
    
    |  | CDH17/Cadherin 17 | 
    
    |  | Mouse | 
    
    |  | Q9R100 | 
    
    
    |  | Phe26-Met786 | 
    
    |  | The protein has a predicted MW of 85.4 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on the Tris-Bis PAGE result. | 
    
    |  | 0 | 
    
    |  | C-His | 
    
    |  | Expi293 | 
    
    
    
    |  | > 95% as determined by Tris-Bis  PAGE; > 95% as determined by HPLC | 
    
    |  | Less than 1EU per ug by the LAL method. | 
    
    |  | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as a protectant before lyophilization. | 
    
    |  | Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. | 
    
    |  | Shipped at ambient temperature. | 
    
    |  | Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. | 
    
    |  |  |