IRBP (161-180)

IRBP(161-180) is a major pathogenic T-cell epitope from interphotoreceptor retinoid-binding protein. It is widely used to induce experimental autoimmune uveoretinitis and to study retina-specific T-cell responses.

• adaptive immune and antigen-presentation research
• MHC/T-cell epitope studies
• autoimmunity or infectious-disease models
• immune assay development

Exact residue boundaries, species origin and MHC restriction are integral to experimental interpretation. Use the sequence-matched epitope required by the model system.

1. Selected peer-reviewed publication