IRBP (1-20), Human

Human IRBP(1-20) contains a major uveitogenic epitope capable of inducing T-cell-mediated experimental autoimmune uveoretinitis. It provides a defined N-terminal retinal autoantigen for ocular immunology research.

• adaptive immune and antigen-presentation research
• MHC/T-cell epitope studies
• autoimmunity or infectious-disease models
• immune assay development

Exact residue boundaries, species origin and MHC restriction are integral to experimental interpretation. Use the sequence-matched epitope required by the model system.

1. Selected peer-reviewed publication