Human TGF-beta RII/TGFBR2 Protein (LTP10692)

Product Name
Human TGF-beta RII/TGFBR2 Protein (LTP10692)
Catalog Number
LTP10692
Quantity
100ug
Price
$406 In stock
Background
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-?) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division.
Description
Recombinant Human TGF-beta RII/TGFBR2 Protein is expressed from Expi293 with mFc (IgG1) tag and Avi tag at C-terminal. It contains Ile24-Asp159.
Target
TGF-beta RII/TGFBR2
Species
Human
Gene/Protein ID
P37173-1
Exact Sequence
Ile24-Asp159
Molecular Weight
The protein has a predicted MW of 44 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on the Tris-Bis PAGE result.
Activity
Immobilized Human TGF-beta RII, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Mature TGF beta 3, Avi Tag with the EC50 of 9.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Tag
C-mFc-Avi
Express System
Expi293
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as a protectant before lyophilization.
Stability and Storage

Reconstituted protein stable at -80 C for 12 months, 4 C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Shipping
Shipped at ambient temperature.
Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration of more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.

Image
Human TGF-beta RII/TGFBR2 Protein (LTP10692)
  • 5 Units in Stock

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